Resveratrol

Resveratrol is a polyphenolic antitoxin found in a variety of plant species, including peanuts, berries, and grapes, most commonly found in the root of polygonum cuspidatum. Resveratrol has been used to treat inflammation in Asia for hundreds of years. In recent years, the health benefits of red wine have been attributed to its presence in grapes. The inspiration comes from an event known as the French Paradox.

The French Paradox was first proposed by an Irish doctor named Samuel Blair in an academic paper published in 1819. The French love food, eat a diet high in calories and cholesterol, and yet have a much lower incidence of cardiovascular disease than their English-speaking counterparts. So why does this happen? According to research, local people often eat with tannin-rich wine to accompany the meal. Red wine contains resveratrol, which prevents blood clots, reduces inflammation, promotes dilation of blood vessels and inhibits bacterial growth.

Resveratrol was discovered in 1924 for the first time in biological experiments. The Japanese found resveratrol in the roots of plants in 1940. In 1976, the British also found resveratrol in wine, it can reach 5-10mg/kg in high quality dry red wine. Resveratrol can be found in wine, because the skins of the grapes used in making wine richly contain resveratrol. In the process of making wine in the traditional handwork method, resveratrol goes into the wine production process with grape skins, finally dissolved gradually along with the release of the alcohol in wine. In the 1980s, people gradually found the existence of resveratrol in more plants, such as cassia seed, polygonum cuspidatum, peanut, mulberry and other plants.

Botanist studies have shown that natural resveratrol is a kind of antitoxin secreted by plants in the face of adversity or pathogen invasion. The synthesis of resveratrol increases sharply when exposed to ultraviolet radiation, mechanical damage and fungal infection, so it is called plant antibiotics. Resveratrol can help plants to fight against external pressures such as trauma, bacteria, infection and ultraviolet radiation, so it is not too much to call it the natural guardian of plants.

Resveratrol has been proved to have antioxidant, anti-free radical, anti-tumor, cardiovascular protection and other effects.
1.Antioxidant, anti-free radical effect- Resveratrol is a natural antioxidant, the most prominent role is to remove or inhibit the generation of free radicals, inhibit lipid peroxidation, and regulate the activities of antioxidant related enzymes.
2.Anti-tumor effect- The anti-tumor effect of resveratrol showed that it could inhibit the initiation, promotion and development of tumor. It can antagonize gastric cancer, breast cancer, liver cancer, leukemia and other tumor cells to varying degrees through various mechanisms.
3.Cardiovascular protection- Resveratrol regulates blood cholesterol levels and reduces the risk of cardiovascular disease by binding to estrogen receptors in the body. Moreover, resveratrol also has anti-platelet agglutination effect, which can prevent platelets from aggregating to form blood clots adhering to the vessel wall, thus inhibiting and alleviating the occurrence and development of cardiovascular diseases.
4.Estrogen effect- Resveratrol is similar in structure to the estrogen diethylstilbestrol, which binds to estrogen receptors and plays the role of estrogen signal transduction.
5.Anti-inflammatory and antimicrobial effects- Resveratrol has inhibitory effect on Staphylococcus aureus, catacoccus, Escherichia coli and Pseudomonas aeruginosa. Anti-inflammatory experimental studies have shown that resveratrol can achieve therapeutic effect by reducing platelet adhesion and changing platelet activity during the anti-inflammatory process.

Our company has been engaged in resveratrol extraction for more than 20 years, has a wealth of production, research and development experience. Resveratrol’s excellent nutritional effect has been widely concerned by various people. Based on market projections, the potential for resveratrol to be used as a supplement is strong, especially for specific diseases. Dietary supplements are one of the most widely used areas of resveratrol, and the beverage industry has been more receptive than the food industry to new food and beverage products, especially energy drinks. In addition, consumers’ preference for natural products will also drive the widespread use of resveratrol in supplements.

According to incomplete statistics, global consumption of resveratrol increased by an average growth rate of 5.59%. Since 2015, the United States has accounted for 76.3 percent of the world’s new resveratrol products, while Europe has accounted for only 15.1 percent. Currently, the vast majority of resveratrol nutritional products come from the United States. The demand for resveratrol is increasing due to greater demand for downstream products.

In line with the concept of being responsible for the society, the enterprise and the employees, Uniwell biotechnology has always attached great importance to the control of the production process and the quality inspection of the products. From raw material procurement, production, packaging, sales and after-sales service, we strictly comply with GMP requirements for management.We have a strong quality assurance team, advanced inspection equipment (HPLC, GC, etc.) and facilities, and established a strict quality management system.

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